[Soft-matter] Soft Matter and Statistical Physics Seminar, 16 Oct 2020

[Maciej Lisicki]

Dear Soft Matter Colleagues and Friends,

On Friday 16 October 2020 we will host a seminar during which

Tomasz Skóra (IChF PAN)

will give a talk

Macromolecular Crowding: How the Shape of Macromolecules Affects Diffusion?

Abstract
Significant fraction of cell’s volume is occupied by various proteins, polysaccharides, RNAs etc. Such crowding substantially reduces the mobility of macromolecules, and affects both thermodynamics and kinetics of intracellular processes. While prior research has mainly focused on the dependence of translational mobility on occupied volume fraction, studies of the effect of crowder shape are still scarce. In this work, we fill this gap by investigating self-diffusion in mixtures of spherical and elongated macromolecules with Fluorescence Correlation Spectroscopy (FCS) and Brownian Dynamics (BD) simulations. Our results emphasize that diffusion in crowded systems is determined not merely by the occupied volume fraction, but that the shape of crowders matters, which is relevant to diverse intracellular environments.

The seminar will be conducted via Zoom
https://zoom.us/j/92987083349?pwd=YTZLSFVWUnJzdE4xS1drR3dqMVFDdz09 <https://zoom.us/j/92987083349?pwd=YTZLSFVWUnJzdE4xS1drR3dqMVFDdz09>
Meeting ID: 929 8708 3349
Passcode: a8QhyS
and will begin at 9:30AM. 

Everyone is very welcome to attend and ask questions over Zoom. A limited number of participants may be present in the seminar room. We would like to ask those interested in attending in person to contact the organisers prior to the seminar to ensure safety.

Maria Ekiel-Jeżewska
Maciej Lisicki
Marek Napiórkowski
Piotr Szymczak

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